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BMP4 Rabbit mAb

Anti-BMP4 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261929

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261929
Product Name:   Anti-BMP4 Rabbit Monoclonal Antibody
Synonyms:   BMP4; BMP2B; DVR4; Bone morphogenetic protein 4; BMP-4; Bone morphogenetic protein 2B; BMP-2B
UNIPROT ID:   P12644
Background:    Bone morphogenetic proteins (BMPs) were first identified as molecules that can induce ectopic bone and cartilage formation. BMPs belongs to the TGF-β superfamily, playing many diverse functions during development. BMPs are synthesized as precursor proteins and then processed by cleavage to release the c-terminal mature BMP. BMPs initiate signaling by binding to a receptor complex containing type I and type II serine/threonine receptor kinases that then phosphorylate Smad (mainly Smad1, 5 and 8), resulting the translocation of Smad into the nucleus. BMP was also reported to activate MAPK pathways in some systems.
Immunogen:    A synthetic peptide of human BMP4
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R01-2G4
MW:    Calculated MW: 47 kDa; Observed MW: 47 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cardiovascular
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of BMP4 in K562, Hela lysates using BMP4 antibody.

Immunocytochemistry analysis of BMP4 (green) in HEPG2 using BMP4 antibody,and DAPI(blue).
          Publications