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Interferon alpha/beta Receptor 1 Rabbit mAb

Anti-Interferon alpha/beta Receptor 1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262419

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262419
Product Name:   Anti-Interferon alpha/beta Receptor 1 Rabbit Monoclonal Antibody
Synonyms:   IFNAR1; IFNAR; Interferon alpha/beta receptor 1; IFN-R-1; IFN-alpha/beta receptor 1; Cytokine receptor class-II member 1; Cytokine receptor family 2 member 1; CRF2-1; Type I interferon receptor 1
UNIPROT ID:   P17181
Background:    Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway.
Immunogen:    A synthetic peptide of human Interferon alpha/beta receptor 1
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R09-7D6
MW:    Calculated MW: 64 kDa; Observed MW: 110-130 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Interferon alpha/beta receptor 1 in K562, Hela lysates using Interferon alpha/beta Receptor 1 antibody.
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