NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N262845 | ||
Product Name: Anti-RPA32 Rabbit Monoclonal Antibody | ||
Synonyms: 60S acidic ribosomal protein P1; AA409079; AI325195; AU020965; HSSB; ik:tdsubc_2g1; M(2)21C; MGC137236; OTTHUMP00000004008; p32; p34; RCJMB04_6d17 replication protein A2; 32kDa; REPA 2; REPA1; REPA2; Replication factor A protein 2; Replication protein A 32 kDa subunit; Replication protein A 32kDa subunit; Replication protein A 34 kDa subunit; Replication protein A; replication protein A1 (70kD); Replication Protein A2 (32kDa); Replication protein A2 32kD; Replication protein A2 32kDa; Replication protein A2; Replication protein A2; 32kDa; RF A; RF-A protein 2; Rf-A2; RFA; RFA2_HUMAN; RP A; RP-A p32; RP-A p34; RP21C; RPA 2; RPA 32; RPA; RPA2; RPA32; RPA34; RPA70; RpLP1; RpP2; xx:tdsubc_2g1; zgc:109822. | ||
UNIPROT ID: P15927 | ||
Background: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. | ||
Immunogen: A synthetic peptide of human RPA32/RPA2 | ||
Applications: WB,IHC-P | ||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Monoclonal | ||
Clone ID: R02-8A3 | ||
MW: Calculated MW: 29 kDa; Observed MW: 29 kDa | ||
Isotype: IgG | ||
Purification: Affinity Purified | ||
Species Reactivity: Human,Rat | ||
Conjugation: Unconjugated | ||
Modification: Unmodified | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
Research Areas: Epigenetics and Nuclear Signaling | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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