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PRAS40 Rabbit mAb

Anti-PRAS40 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263506

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263506
Product Name:   Anti-PRAS40 Rabbit Monoclonal Antibody
Synonyms:   AKT1S1; PRAS40; Proline-rich AKT1 substrate 1; 40 kDa proline-rich AKT substrate
UNIPROT ID:   Q96B36
Background:    PRAS40 interacts with Raptor in mTOR complex 1 (mTORC1) in insulin-deprived cells and inhibits the activation of the mTORC1 pathway mediated by the cell cycle protein Rheb. Phosphorylation of PRAS40 by Akt at Thr246 relieves PRAS40 inhibition of mTORC1. mTORC1 in turn phosphorylates PRAS40 at Ser183.
Immunogen:    A synthetic peptide of human PRAS40
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R05-3A5
MW:    Calculated MW: 27 kDa; Observed MW: 40 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of PRAS40 in Hela, A549, C6 lysates using PRAS40 antibody.
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