NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$239.00
Cat. #: 26020 |
Gene Symbol: RAN |
Description: Anti-Ran-Mouse Monoclonal Antibody |
Background: Ran (Ras-related nuclear protein) is a member of the Ras-superfamily GTPases. Ran is involved in the transport of proteins across the nuclear envelope, as well as in microtubule organization during mitosis. |
Immunogen: Recombinant full length protein of Ran |
Applications: ELISA, WB, IP, IHC |
Recommended Dilutions: ELISA: 1:1000-1:5000 WB: 1:100-1:2000 IP: 1 µg for 1~2 mg total cellular proteins IHC: 1:100 dilution |
Concentration: 1 mg/ml |
Host Species: Mouse |
Format: Liquid |
Clonality: Monoclonal |
Isotype: IgG |
Purity: Purified from ascites |
Preservative: No |
Constituents: PBS (without Mg 2+ and Ca 2+ ), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Anti-Ran antibody recognizes Ran of vertebrates. |
Storage Conditions: Store at -20°C. Avoid repeated freezing and thawing |