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Human ADGRG1 Full Length Protein

Human ADGRG1 Full Length Protein-Synthetic Nanodisc
5/5

$4,400.00

Cat.#:  11085

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11085
Product Name:   Human ADGRG1 Full Length Protein
Size :    10 µg; 50 µg and 100 µg
Synonyms:   BFPP; BPPR; GPR56; TM7LN4; TM7XN1
Target:    ADGRG1
UNIPROT ID:    Q9Y653
Description:    Human ADGRG1 Full Length Protein-Synthetic Nanodisc
Background:     A member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria.
Species/Host:    HEK293
Molecular Weight:    The human full length ADGRG1 protein has a MW of 77.7 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Protein Families:    Druggable Genome, GPCR, Transmembrane
Protein Pathways:    N.A.

Figure 1. Elisa plates were pre-coated with Flag Tag ADGRG1-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with ADGRG1-Nanodisc is 1.419ng/ml.

Figure 2. Human ADGRG1-Nanodisc, Flag Tag on SDS-PAGE
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