Email: info@neweastbio.com   |  Call: 6109452007

ADAM10 Rabbit pAb

Anti-ADAM10 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N226015

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N226015
Product Name:   Anti-ADAM10 Rabbit pAb
Synonyms:   CDw156; CD156c; ADAM10; KUZ; MADM
UNIPROT ID:   O14672
Background:    The ADAM10 prodomain acts as a chaperone that stabilizes mature ADAM protein folding, and prevents target-protein shedding through inhibition of ADAM10 proteinase activity. Mature ADAM10 is the major α-secretase responsible for cleavage of Notch, APP, cadherins, and prion protein. The ADAM10 protein cleaves receptor tyrosine kinases and their associated ligands and displays a wide range of regulatory functions across related signaling pathways.
Immunogen:    A synthetic peptide of human ADAM10
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 84 kDa; Observed MW: 90,68 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of ADAM10 in NTERA-2 lysates using ADAM10 antibody.
          Publications