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ADAM11 Rabbit pAb

Anti-ADAM11 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220264

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220264
Product Name:   Anti-ADAM11 Rabbit Polyclonal Antibody
Synonyms:   MDC
UNIPROT ID:   O75078 (Gene Accession – NP_002381 )
Background:    This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.
Immunogen:    Synthetic peptide of human ADAM11
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 220264(ADAM11 Antibody) at a dilution of 1/25(Cytoplasm, Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the synthetic peptide and then with 220264(Anti-ADAM11 Antibody) at dilution 1/25.

The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using 220264(Anti-ADAM11 Antibody) at a dilution of 1/25.

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with synthetic peptide and then with D261230(Anti-ADAM11 Antibody) at dilution 1/25.

Gel: 10%SDS-PAGE, Lysate: 50 μg;
Lane: Hela cells;
Primary antibody: 220264(ADAM11 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 10 minutes
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