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CHD4 Rabbit pAb

Anti-CHD4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S222398

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S222398
Product Name:   Anti-CHD4 Rabbit Polyclonal Antibody
Synonyms:   CHD-4; Mi-2b; SIHIWES; Mi2-BETA
UNIPROT ID:   Q14839 (Gene Accession – NP_001264 )
Background:    The product of this gene belongs to the SNF2/RAD54 helicase family. It represents the main component of the nucleosome remodeling and deacetylase complex and plays an important role in epigenetic transcriptional repression. Patients with dermatomyositis develop antibodies against this protein. Somatic mutations in this gene are associated with serous endometrial tumors. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen:    Synthetic peptide of human CHD4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 50-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology, Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 222398(CHD4 Antibody) at a dilution of 1/50(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the synthetic peptide and then with 222398(Anti-CHD4 Antibody) at dilution 1/50.
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