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EGFR Rabbit mAb

Anti-EGFR Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N261661

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N261661
Product Name:   Anti-EGFR Rabbit Monoclonal Antibody
Synonyms:   EGFR; ERBB; ERBB1; HER1; Epidermal growth factor receptor; Proto-oncogene c-ErbB-1; Receptor tyrosine-protein kinase erbB-1
UNIPROT ID:   P00533
Background:    EGFR is a receptor tyrosine kinase. Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation.
Immunogen:    A synthetic peptide of human EGFR
Applications:    WB,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R03-6B1
MW:    Calculated MW: 134 kDa; Observed MW: 175 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunocytochemistry analysis of EGFR(green) in Hela using EGFR antibody,and DAPI(blue)

Western blot analysis of EGFR in mouse liver lysates using EGFR antibody.

Western blot analysis of EGFR in Hela lysates using EGFR antibody.
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