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ELAVL1 Rabbit pAb

Anti-ELAVL1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216489

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216489
Product Name:   Anti-ELAVL1 Rabbit Polyclonal Antibody
Synonyms:   HUR; Hua; MelG; ELAV1
UNIPROT ID:   Q15717 (Gene Accession – BC003376 )
Background:    The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3′ untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding AREs, the ELAVL family of proteins play a role in stabilizing ARE-containing mRNAs. This gene has been implicated in a variety of biological processes and has been linked to a number of diseases, including cancer. It is highly expressed in many cancers, and could be potentially useful in cancer diagnosis, prognosis, and therapy.
Immunogen:    Fusion protein of human ELAVL1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human lung cancer tissue using 216489(ELAVL1 Antibody) at a dilution of 1/50(Nucleus and Cytoplasm ).

In comparision with the IHC on the left, the same paraffin-embedded Human lung cancer tissue is first treated with the fusion protein and then with 216489(Anti-ELAVL1 Antibody) at dilution 1/50.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 216489(Anti-ELAVL1 Antibody) at a dilution of 1/50.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with fusion protein and then with D220589(Anti-ELAVL1 Antibody) at dilution 1/50.

Gel: 10%SDS-PAGE, Lysate: 40 μg;
Lane 1-4: Hela cells, NIH/3T3 cells, A172 cells, A431 cells;
Primary antibody: 216489(ELAVL1 Antibody) at dilution 1/800;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 seconds
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