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EYA1/4 Rabbit pAb

Anti-EYA1/4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225051

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225051
Product Name:   Anti-EYA1/4 Rabbit pAb
Synonyms:   Eyes absent homolog 1; Eyes absent homolog 4
UNIPROT ID:   Q99502/O95677
Background:    Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates ‘Tyr-142’ of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. ‘Tyr-142’ phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress.
Immunogen:    Synthetic peptide from human protein at AA range: 271-320
Applications:    IHC-P,ELISA
Recommended Dilutions:    IHC: 1/50-1/100 ELISA: 1/10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:   
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemical analysis of paraffin-embedded Human tonsils using EYA1/4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human kidney using EYA1/4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human brain using EYA1/4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded Human brain using EYA1/4 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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