Email: info@neweastbio.com   |  Call: 6109452007

Fibrillarin Rabbit mAb

Anti-Fibrillarin Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262221

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262221
Product Name:   Anti-Fibrillarin Rabbit Monoclonal Antibody
Synonyms:   FIB; FLRN; Nop1; RNU3IP1
UNIPROT ID:   P22087
Background:    Fibrillarin is a 2′-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2′-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development.
Immunogen:    A synthetic peptide of human Fibrillarin
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R09-7E5
MW:    Calculated MW: 34 kDa; Observed MW: 34 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Tags & Cell Markers
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Fibrillarin in K562, C6, 3T3 lysates using Fibrillarin antibody.
          Publications