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hnRNP K Rabbit mAb

Anti-hnRNP K Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262351

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262351
Product Name:   Anti-hnRNP K Rabbit Monoclonal Antibody
Synonyms:   HNRNPK; HNRPK; Heterogeneous nuclear ribonucleoprotein K; hnRNP K; Transformation up-regulated nuclear protein; TUNP
UNIPROT ID:   P61978
Background:    Facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP K contains three unique structural motifs termed KH domains that bind poly(C) DNA and RNA sequences. Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis, transcriptional regulation, and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor.
Immunogen:    A synthetic peptide of human hnRNP K
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-0A0
MW:    Calculated MW: 51 kDa; Observed MW: 58 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat,Hamster
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using hnRNP K antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of hnRNP K in 3T3, MEF lysates using hnRNP K antibody.

Western blot analysis of hnRNP K in C6, CHO-K1, Hela lysates using hnRNP K antibody.

Immunocytochemistry analysis of hnRNP K (green) in MCF-7 using hnRNP K antibody,and DAPI(blue).
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