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Insulin Degrading Enzyme Rabbit mAb

Anti-Insulin Degrading Enzyme Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263625

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263625
Product Name:   Anti-Insulin Degrading Enzyme Rabbit Monoclonal Antibody
Synonyms:   INSULYSIN; Insulin degrading enzyme; IDE
UNIPROT ID:   P14735
Background:    This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid.
Immunogen:    A synthesized peptide derived from human IDE
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R07-6D3
MW:    Calculated MW: 118 kDa; Observed MW: 118 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Insulin Degrading Enzyme/IDE antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Insulin Degrading Enzyme/IDE in Hela, A549, HL-60, U2OS lysates using Insulin Degrading Enzyme antibody.
          Publications