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IRF1 Rabbit mAb

Anti-IRF1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262423

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262423
Product Name:   Anti-IRF1 Rabbit Monoclonal Antibody
Synonyms:   IRF1; Interferon regulatory factor 1; IRF-1
UNIPROT ID:   P10914
Background:    Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and activates those genes. Acts as a tumor suppressor. Defects in IRF1 are a cause of gastric cancer (GASC) [MIM:613659]; also called gastric cancer intestinal or stomach cancer. Gastric cancer is a malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body.
Immunogen:    Recombinant protein of human IRF1
Applications:    WB,IHC-F,IHC-P,ICC/IF,IP
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R08-1B4
MW:    Calculated MW: 37 kDa; Observed MW: 48 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer tissue using IRF1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunocytochemistry analysis of IRF1 (green) in U87-MG using IRF1 antibody,and DAPI(blue).

Western blot analysis of IRF1 in K562, C6, 3T3 lysates using IRF1 antibody.
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