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KLF17 Rabbit pAb

Anti-KLF17 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S217096

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S217096
Product Name:   Anti-KLF17 Rabbit Polyclonal Antibody
Synonyms:   ZNF393; Zfp393; RP4-675G8.1
UNIPROT ID:   Q5JT82 (Gene Accession – BC049844 )
Background:    Krueppel-like factor 17 is a protein that in humans is encoded by the KLF17 gene. Transcription repressor that binds to the promoter of target genes and prevents their expression. Acts as a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Specifically binds the 5′-CACCC-3′ sequence in the promoter of ID1, a key metastasis regulator in breast cancer, and repress its expression. May be a germ cell-specific transcription factor that plays important roles in spermatid differentiation and oocyte development.
Immunogen:    Fusion protein of human KLF17
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 25-100; ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colon cancer tissue using 217096(KLF17 Antibody) at a dilution of 1/30(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colon cancer tissue is first treated with the fusion protein and then with 217096(Anti-KLF17 Antibody) at dilution 1/30.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 217096(Anti-KLF17 Antibody) at a dilution of 1/30.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D221780(Anti-KLF17 Antibody) at dilution 1/30.
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