NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N262461 | ||
Product Name: Anti-LAMP2A Rabbit Monoclonal Antibody | ||
Synonyms: LAMP2; Lysosome-associated membrane glycoprotein 2; LAMP-2; Lysosome-associated membrane protein 2; CD107 antigen-like family member B; CD107b | ||
UNIPROT ID: P13473 | ||
Background: Lysosomal-associated membrane protein 2 (LAMP2, synonyms: LAMPB, CD107b) is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. LAMP2 may plays a role in tumor cell metastasis. It may also functions in the protection, maintenance, and adhesion of the lysosome.Prior to posttranslational modification, Lysosome Associated Membrane Protein 2 (LAMP2) is a ~45 kDa polypeptide. | ||
Immunogen: A synthetic peptide of human LAMP2A | ||
Applications: WB,IHC-P,IP | ||
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 | ||
Host Species: Rabbit | ||
Clonality: Rabbit Monoclonal | ||
Clone ID: R03-2J8 | ||
MW: Calculated MW: 45 kDa; Observed MW: 110 kDa | ||
Isotype: IgG | ||
Purification: Affinity Purified | ||
Species Reactivity: Human,Mouse | ||
Conjugation: Unconjugated | ||
Modification: Unmodified | ||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide | ||
Research Areas: Tags & Cell Markers | ||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||
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