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Ly6a Rabbit pAb

Anti-Ly6a Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S214013

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S214013
Product Name:   Anti-Ly6a Rabbit Polyclonal Antibody
Synonyms:   TAP; Sca1; Sca-1; Ly-6A.2; Ly-6A/E; Ly-6E.1
UNIPROT ID:   P05533 (Gene Accession – NP_034868 )
Background:    The activity of natural killer (NK) cells is regulated by members of multiple receptor families that recognize class I MHC molecules, such as the killer cell inhibitory receptor/leukocyte immunoglobulin-like receptor (KIR/LIR) family and the C-type lectin superfamily. The Ly-6 alloantigens represent a family of phosphatidylinositol anchored proteins that play a role in the process of T lymphocyte activation. Ly-6 expression is commonly induced on T and B lymphocytes after activation by mitogens. Ly-6A/E is a phosphatidylinositol-linked transmembrane member of the Ly-6 family that is produced in humans after 4 weeks of age. ?-interferon and TNF regulate Ly-6A/E at the level of transcription and mRNA stabilization in certain thymocytes and T-cells.
Immunogen:    Synthetic peptide of mouse Ly6a
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 20-100; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Immunology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Mouse liver tissue using 214013(Ly6a Antibody) at a dilution of 1/25(Cell membrane).
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