NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: S213661 | ||||
Product Name: Anti-MYF5 Rabbit Polyclonal Antibody | ||||
Synonyms: bHLHc2 | ||||
UNIPROT ID: P13349 (Gene Accession – NP_005584 ) | ||||
Background: Myogenic factor 5 is a protein that in humans is encoded by the MYF5 gene. It is a protein with a key role in regulating muscle differentiation or myogenesis. Without Myf5 and MyoD, myogenic cells will fail to progress normally during the determination stage of myogenesis. Myf5 belongs to a family of proteins known as myogenic regulatory factors (MRFs). These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation. MRF family members include Myf5, MyoD (Myf3), myogenin, and MRF4 (Myf6). | ||||
Immunogen: Synthetic peptide of human MYF5 | ||||
Applications: ELISA, IHC | ||||
Recommended Dilutions: IHC: 25-100; ELISA: 1000-2000 | ||||
Host Species: Rabbit | ||||
Clonality: Rabbit Polyclonal | ||||
Isotype: Immunogen-specific rabbit IgG | ||||
Purification: Antigen affinity purification | ||||
Species Reactivity: Human, Mouse | ||||
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol | ||||
Research Areas: Epigenetics and Nuclear Signaling, Stem Cells, Developmental Biology | ||||
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing | ||||
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