NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N261781 |
Product Name: Anti-Neurofilament light polypeptide Rabbit Monoclonal Antibody |
Synonyms: NFL; NF-L; NF68; CMT1F; CMT2E; CMTDIG; PPP1R110 |
UNIPROT ID: P08551 |
Background: Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber.MiscellaneousNF-L is the most abundant of the three neurofilament proteins and, like the other nonepithelial intermediate filament proteins, it can form homopolymeric 10-nm filaments. |
Immunogen: Recombinant protein of mouse 68kDa Neurofilament |
Applications: WB,IHC-P,IP |
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IP: 1/20 |
Host Species: Rabbit |
Clonality: Rabbit Monoclonal |
Clone ID: R04-7H3 |
MW: Calculated MW: 62 kDa; Observed MW: 68 kDa |
Isotype: IgG |
Purification: Affinity Purified |
Species Reactivity: Mouse |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: NeuroscienceyyyyyMature Neurons |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of 68kDa Neurofilament in mouse brain lysates using Neurofilament light polypeptide antibody. |