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NIT1 Rabbit mAb

Anti-NIT1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262611

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262611
Product Name:   Anti-NIT1 Rabbit Monoclonal Antibody
Synonyms:   Nitrilase homolog 1
UNIPROT ID:   Q86X76
Background:    Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells; this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells.
Immunogen:    A synthetic peptide of human NIT1
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R09-9D7
MW:    Calculated MW: 36 kDa; Observed MW: 36 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of NIT1 in Hela, 293T, Jurkat, 3T3 lysates using NIT1 antibody.
          Publications