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NOLC1 Rabbit mAb

Anti-NOLC1 Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262618

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262618
Product Name:   Anti-NOLC1 Rabbit Monoclonal Antibody
Synonyms:   P130; NOPP130; NOPP140; NS5ATP13
UNIPROT ID:   Q14978
Background:    Nucleolar protein that acts as a regulator of RNA polymerase I by connecting RNA polymerase I with enzymes responsible for ribosomal processing and modification (PubMed:10567578, PubMed:26399832). Required for neural crest specification: following monoubiquitination by the BCR(KBTBD8) complex, associates with TCOF1 and acts as a platform to connect RNA polymerase I with enzymes responsible for ribosomal processing and modification, leading to remodel the translational program of differentiating cells in favor of neural crest specification (PubMed:26399832). Involved in nucleologenesis, possibly by playing a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus (PubMed:9016786). It has intrinsic GTPase and ATPase activities (PubMed:9016786).
Immunogen:    A synthetic peptide of human NOLC1
Applications:    WB,IHC-F,IHC-P,ICC/IF
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R03-7F1
MW:    Calculated MW: 74 kDa; Observed MW: 110 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Unmodified
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using NOLC1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of NOLC1 in Jurkat lysates using NOLC1 antibody.

Immunocytochemistry analysis of NOLC1 (green) in Hela using NOLC1 antibody,and DAPI(blue)
          Publications