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PARP3 Rabbit pAb

Anti-PARP3 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S220781

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S220781
Product Name:   Anti-PARP3 Rabbit Polyclonal Antibody
Synonyms:   IRT1; ARTD3; ADPRT3; ADPRTL2; ADPRTL3; PADPRT-3
UNIPROT ID:   Q9Y6F1 (Gene Accession – NP_001003931 )
Background:    The protein encoded by this gene belongs to the PARP family. These enzymes modify nuclear proteins by poly-ADP-ribosylation, which is required for DNA repair, regulation of apoptosis, and maintenance of genomic stability. This gene encodes the poly(ADP-ribosyl)transferase 3, which is preferentially localized to the daughter centriole throughout the cell cycle. Alternatively spliced transcript variants encoding different isoforms have been identified.
Immunogen:    Synthetic peptide of human PARP3
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 20-100;WB: 200-1000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 220781(PARP3 Antibody) at a dilution of 1/20(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the synthetic peptide and then with 220781(Anti-PARP3 Antibody) at dilution 1/20.

The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using 220781(Anti-PARP3 Antibody) at a dilution of 1/20.

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with synthetic peptide and then with D262013(Anti-PARP3 Antibody) at dilution 1/20.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane: Human cerebrum tissue lysate;
Primary antibody: 220781(PARP3 Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 minute
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