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PBXIP1 Rabbit pAb

Anti-PBXIP1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218777

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218777
Product Name:   Anti-PBXIP1 Rabbit Polyclonal Antibody
Synonyms:   HPIP
UNIPROT ID:   Q96AQ6 (Gene Accession – BC016852 )
Background:    The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.
Immunogen:    Fusion protein of human PBXIP1
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 218777(PBXIP1 Antibody) at a dilution of 1/40(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 218777(Anti-PBXIP1 Antibody) at dilution 1/40.
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