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Phospho-alpha Synuclein (Ser129) Rabbit pAb

Anti-Phospho-alpha Synuclein (Ser129) Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N225297

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N225297
Product Name:   Anti-Phospho-alpha Synuclein (Ser129) Rabbit pAb
Synonyms:   SNCA; NACP; PARK1; Alpha-synuclein; Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP
UNIPROT ID:   P37840
Background:    May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. Genetic alterations of SNCA resulting in aberrant polymerization into fibrils, are associated with several neurodegenerative diseases (synucleinopathies).
Immunogen:    Synthetic peptide of human SNCA
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 14 kDa; Observed MW: 18 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse,Rat
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Neuroscience
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human brain using Synuclein (Phospho-Ser129) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

Western blot analysis of Phospho-alpha Synuclein (Ser129) in mouse brain lysates using Phospho-alpha Synuclein (Ser129) antibody.
          Publications