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Phospho-GCN2 (Thr667) Rabbit pAb

Anti-Phospho-GCN2 (Thr667) Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  N226077

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N226077
Product Name:   Anti-Phospho-GCN2 (Thr667) Rabbit pAb
Synonyms:   GCN2-like protein; GCN2; KIAA1338; EIF2AK4
UNIPROT ID:   Q9P2K8
Background:    This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2.
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Thr667 of human GCN2
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Clone ID:   
MW:    Calculated MW: 187 kDa; Observed MW: 220 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-GCN2 (Thr667) in Hela, HepG2, 293T lysates using Phospho-GCN2 (Thr667) antibody.
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