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Phospho-MEK4 (Ser80) Rabbit mAb

Anti-Phospho-MEK4 (Ser80) Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N263177

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N263177
Product Name:   Anti-Phospho-MEK4 (Ser80) Rabbit Monoclonal Antibody
Synonyms:   MAP2K4; JNKK1; MEK4; MKK4; PRKMK4; SEK1; SERK1; SKK1; Dual specificity mitogen-activated protein kinase kinase 4; MAP kinase kinase 4; MAPKK 4; JNK-activating kinase 1; MAPK/ERK kinase 4; MEK 4; SAPK/ERK kinase 1; SEK1; Stress-activated pro
UNIPROT ID:   P45985
Background:    This gene encodes a member of the mitogen-activated protein kinase (MAPK) family. Members of this family act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. They form a three-tiered signaling module composed of MAPKKKs, MAPKKs, and MAPKs. This protein is phosphorylated at serine and threonine residues by MAPKKKs and subsequently phosphorylates downstream MAPK targets at threonine and tyrosine residues. A similar protein in mouse has been reported to play a role in liver organogenesis. A pseudogene of this gene is located on the long arm of chromosome X. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Ser80 of human MEK4/MKK4
Applications:    WB,IP
Recommended Dilutions:    WB: 1/500-1/1000 IP: 1/20
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R03-5C4
MW:    Calculated MW: 44 kDa; Observed MW: 44 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Signal Transduction
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Western blot analysis of Phospho-MEK4/MKK4 (Ser80) in A549, MCF-7, U251 lysates using Phospho-MEK4/MKK4 (Ser80) antibody.

Western blot analysis of Phospho-MEK4/MKK4 (Ser80) in 3T3 lysates using Phospho-MEK4 (Ser80) antibody.
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