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Phospho-mTOR (Ser2448) Rabbit mAb

Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody
5/5

$349.00

Cat.#:  N262549

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   N262549
Product Name:   Anti-Phospho-mTOR (Ser2448) Rabbit Monoclonal Antibody
Synonyms:   MTOR; FRAP; FRAP1; FRAP2; RAFT1; RAPT1; Serine/threonine-protein kinase mTOR; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic tar
UNIPROT ID:   P42345
Background:    An atypical kinase belonging to the PIKK family of kinases. Controls cell growth through protein synthesis regulation. Downstream of PI3K/Akt pathway and required for cell survival. Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex.
Immunogen:    A synthetic phosphopeptide corresponding to residues surrounding Ser2448 of human mTOR
Applications:    WB,IHC-P
Recommended Dilutions:    WB: 1/500-1/1000 IHC: 1/50-1/100
Host Species:    Rabbit
Clonality:    Rabbit Monoclonal
Clone ID:    R08-7G7
MW:    Calculated MW: 289 kDa; Observed MW: 289 kDa
Isotype:    IgG
Purification:    Affinity Purified
Species Reactivity:    Human,Mouse
Conjugation:    Unconjugated
Modification:    Phosphorylated
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide
Research Areas:    Hypoxia Signal Transductionyyyyy Hypoxia-induced
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Phospho-mTOR (Ser2448) antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Western blot analysis of Phospho-mTOR (Ser2448) in Hela, Hela+EGF lysates using Phospho-mTOR (Ser2448) antibody.

Western blot analysis of mTOR (Phospho-Ser2448) in 3t3 lysates using mTOR (Phospho-Ser2448) antibody.
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