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QDPR Rabbit pAb

Anti-QDPR Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S212543

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S212543
Product Name:   Anti-QDPR Rabbit Polyclonal Antibody
Synonyms:   DHPR; PKU2; HDHPR; SDR33C1
UNIPROT ID:   P09417 (Gene Accession – BC000576 )
Background:    This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
Immunogen:    Fusion protein of human QDPR
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Metabolism
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human liver cancer tissue using 212543(QDPR Antibody) at a dilution of 1/70(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human liver cancer tissue is first treated with the fusion protein and then with 212543(Anti-QDPR Antibody) at dilution 1/70.

The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using 212543(Anti-QDPR Antibody) at a dilution of 1/70.

In comparision with the IHC on the left, the same paraffin-embedded Human ovarian cancer tissue is first treated with fusion protein and then with D125353(Anti-QDPR Antibody) at dilution 1/70.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane 1-5: Mouse liver tissue, Mouse brain tissue, Rat brain tissue, Rat liver tissue and Human fetal liver tissue lysates;
Primary antibody: 212543(QDPR Antibody) at dilution 1/800;
Secondary antibody: HRP-conjugated Goat anti rabbit IgG at 1/5000 dilution;
Exposure time: 30 seconds
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