NewEast Biosciences pioneered the research and development of the antibodies for GTPases and mutated Oncogene ten years ago. GTPases involve (1) signal transduction in response to activation of cell surface receptors, including transmembrane receptors such as those mediating taste, smell and vision, (2) protein biosynthesis at the ribosome, (3) regulation of cell differentiation, proliferation, division and movement, (4) translocation of proteins through membranes, (5) transport of vesicles within the cell, and vesicle-mediated secretion and uptake, through GTPase control of vesicle coat assembly. An oncogene is a gene that has the potential to cause cancer.
We offer three unique categories of antibodies, which (1) recognize only the active configuration of GTPase (not the inactive one), (2) mutated Oncogene (not mild type) and (3) have super affinity for cAMP and cGMP (no acetylation required). We have over one thousand peer reviewed articles cited our products.
$349.00
Cat.#: N262897 |
Product Name: Anti-SODD Rabbit Monoclonal Antibody |
Synonyms: BAG4; SODD; BAG family molecular chaperone regulator 4; BAG-4; Bcl-2-associated athanogene 4; Silencer of death domains |
UNIPROT ID: O95429 |
Background: Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release . Prevents constitutive TNFRSF1A signaling. Negative regulator of PRKN translocation to damaged mitochondria. |
Immunogen: A synthetic peptide of human Silencer of Death Domain |
Applications: WB,IHC-F,IHC-P,ICC/IF |
Recommended Dilutions: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 |
Host Species: Rabbit |
Clonality: Rabbit Monoclonal |
Clone ID: R06-6J7 |
MW: Calculated MW: 50 kDa; Observed MW: 70 kDa |
Isotype: IgG |
Purification: Affinity Purified |
Species Reactivity: Human |
Conjugation: Unconjugated |
Modification: Unmodified |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.3 containing 50% glycerol, 0.5% BSA and 0.02% sodium azide |
Research Areas: Cell Biology |
Storage & Shipping: Store at -20°C. Avoid repeated freezing and thawing |
Western blot analysis of Silencer of Death Domain in MOLT4 lysates using SODD antibody. |