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STAG2 Rabbit pAb

Anti-STAG2 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S211523

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S211523
Product Name:   Anti-STAG2 Rabbit Polyclonal Antibody
Synonyms:   SA2; SA-2; SCC3B; bA517O1.1
UNIPROT ID:   Q8N3U4 (Gene Accession – BC001765 )
Background:    The protein encoded by this gene is a subunit of the cohesin comple,x which regulates the separation of sister chromatids during cell division. Targeted inactivation of this gene results in chromatid cohesion defects and aneuploidy, suggesting that genetic disruption of cohesin is a cause of aneuploidy in human cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human STAG2
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 25-100;WB: 200-1000;ELISA: 1000-2000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human esophagus cancer tissue using 211523(STAG2 Antibody) at a dilution of 1/35(Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human esophagus cancer tissue is first treated with the fusion protein and then with 211523(Anti-STAG2 Antibody) at dilution 1/35.

The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using 211523(Anti-STAG2 Antibody) at a dilution of 1/35.

In comparision with the IHC on the left, the same paraffin-embedded Human breast cancer tissue is first treated with fusion protein and then with D123087(Anti-STAG2 Antibody) at dilution 1/35.

Gel: 6%SDS-PAGE, Lysate: 40 μg;
Lane: MCF7 cells;
Primary antibody: 211523(STAG2 Antibody) at dilution 1/300;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 5 seconds
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