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TCIM Rabbit pAb

Anti-TCIM Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218796

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218796
Product Name:   Anti-TCIM Rabbit Polyclonal Antibody
Synonyms:   TC1; TC-1; C8orf4
UNIPROT ID:   Q9NR00 (Gene Accession – BC020623 )
Background:    This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011]
Immunogen:    Fusion protein of human TCIM
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human gastric cancer tissue using 218796(TCIM Antibody) at a dilution of 1/55(Nucleus and Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human gastric cancer tissue is first treated with the fusion protein and then with 218796(Anti-TCIM Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 218796(Anti-TCIM Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with fusion protein and then with D225209(Anti-TCIM Antibody) at dilution 1/55.
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