Subtotal:
$239.00
$659.00
| Cat.#: 12196 |
| Product Name: Mouse BAFF Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: B-cell-activating factor;CD257;Tnfsf13b;Baff |
| Target: BAFF |
| UNIPROT ID: Q9WU72 |
| Description: Recombinant mouse BAFF protein with N-terminal human Fc tag |
| Background: Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity. A third B-cell specific BAFF-receptor (BAFFR/BR3) promotes the survival of mature B-cells and the B-cell response.[UniProtKB/Swiss-Prot Function] |
| Species/Host: HEK293 |
| Molecular Weight: The protein has a predicted molecular mass of 46.8 kDa after removal of the signal peptide. The apparent molecular mass of hFc-mBAFF is approximately 40-55 kDa due to glycosylation. |
| Molecular Characterization: hFc(Glu99-Ala330) Mouse BAFF(Ala127-Leu309) |
| Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure 1. Mouse BAFF Protein, hFc Tag on SDS-PAGE under reducing condition. |
