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UBR4 Rabbit pAb

Anti-UBR4 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S221576

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S221576
Product Name:   Anti-UBR4 Rabbit Polyclonal Antibody
Synonyms:   p600; ZUBR1; RBAF600
UNIPROT ID:   Q5T4S7 (Gene Accession – NP_065816 )
Background:    The protein encoded by this gene is an E3 ubiquitin-protein ligase that interacts with the retinoblastoma-associated protein in the nucleus and with calcium-bound calmodulin in the cytoplasm. The encoded protein appears to be a cytoskeletal component in the cytoplasm and part of the chromatin scaffold in the nucleus. In addition, this protein is a target of the human papillomavirus type 16 E7 oncoprotein.
Immunogen:    Synthetic peptide of human UBR4
Applications:    ELISA, IHC
Recommended Dilutions:    IHC: 40-200; ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse, Rat
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Signal Transduction, Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human colorectal cancer tissue using 221576(UBR4 Antibody) at a dilution of 1/55(Cytoplasm).

In comparision with the IHC on the left, the same paraffin-embedded Human colorectal cancer tissue is first treated with the synthetic peptide and then with 221576(Anti-UBR4 Antibody) at dilution 1/55.

The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using 221576(Anti-UBR4 Antibody) at a dilution of 1/55.

In comparision with the IHC on the left, the same paraffin-embedded Human tonsil tissue is first treated with synthetic peptide and then with D263223(Anti-UBR4 Antibody) at dilution 1/55.
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