Email: info@neweastbio.com   |  Call: 6109452007

VHL Rabbit pAb

Anti-VHL Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S216875

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S216875
Product Name:   Anti-VHL Rabbit Polyclonal Antibody
Synonyms:   RCA1; VHL1; pVHL; HRCA1
UNIPROT ID:   P40337 (Gene Accession – BC058831 )
Background:    This gene encodes a component of a ubiquitination complex. The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. In addition to oxygen-related gene expression, this protein plays a role in many other cellular processes including cilia formation, cytokine signaling, regulation of senescence, and formation of the extracellular matrix. Variants of this gene are associated with von Hippel-Lindau syndrome, pheochromocytoma, erythrocytosis, renal cell carcinoma, and cerebellar hemangioblastoma.
Immunogen:    Fusion protein of human VHL
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 50-200;WB: 500-2000;ELISA: 2000-5000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling, Cancer, Cardiovascular, Metabolism, Cell Biology
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin-embedded Human breast cancer tissue using 216875(VHL Antibody) at a dilution of 1/40(Cytoplasm and Nucleus).

Immunohistochemistry analysis of paraffin-embedded Human colorectal cancer tissue using 216875(Anti-VHL Antibody) at a dilution of 1/40.

Gel: 12%SDS-PAGE, Lysate: 40 μg;
Lane: Human fetal brain tissue lysate;
Primary antibody: 216875(VHL Antibody) at dilution 1/200;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 1 second
          Publications