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ZPR1 Rabbit pAb

Anti-ZPR1 Rabbit Polyclonal Antibody
5/5

$349.00

Cat.#:  S218239

   Size:   100 μl

In Stock

          Product Description          
Cat.#:   S218239
Product Name:   Anti-ZPR1 Rabbit Polyclonal Antibody
Synonyms:   ZNF259
UNIPROT ID:   O75312 (Gene Accession – BC004256 )
Background:    The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene.
Immunogen:    Fusion protein of human ZPR1
Applications:    ELISA, WB, IHC
Recommended Dilutions:    IHC: 30-150;WB: 500-2000;ELISA: 5000-10000
Host Species:    Rabbit
Clonality:    Rabbit Polyclonal
Isotype:    Immunogen-specific rabbit IgG
Purification:    Antigen affinity purification
Species Reactivity:    Human, Mouse
Constituents:    PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.05% Sodium Azide and 40% glycerol
Research Areas:    Epigenetics and Nuclear Signaling
Storage & Shipping:    Store at -20°C. Avoid repeated freezing and thawing

Immunohistochemistry analysis of paraffin embedded Human thyroid cancer tissue using 218239(ZPR1 Antibody) at a dilution of 1/40(Cytoplasm and Nucleus).

In comparision with the IHC on the left, the same paraffin-embedded Human thyroid cancer tissue is first treated with the fusion protein and then with 218239(Anti-ZPR1 Antibody) at dilution 1/40.

The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using 218239(Anti-ZPR1 Antibody) at a dilution of 1/40.

In comparision with the IHC on the left, the same paraffin-embedded Human prostate cancer tissue is first treated with fusion protein and then with D224012(Anti-ZPR1 Antibody) at dilution 1/40.

Gel: 8%SDS-PAGE, Lysate: 40 μg;
Lane 1-5: Hela, HEPG2, 231, A431 and Jurkat cell lysates;
Primary antibody: 218239(ZPR1 Antibody) at dilution 1/400;
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution;
Exposure time: 20 seconds
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