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ATM(R3008H)

Anti-ATM(R3008H) Mouse Monoclonal Antibody
5/5

$495.00

Cat.#:  26140

   Size:   100 μl

In Stock

          Product Description          

ATM(R3008H)

Cat. #:   26140
Gene Symbol:  ATM
Description:   Anti-ATM(R3008H) Mouse Monoclonal Antibody
Background:   Ataxia telangiectasia mutated (ATM) is a serine/threonine protein kinase that is recruited and activated by DNA double-strand breaks. It phosphorylates several key proteins that initiate activation of the DNA damage checkpoint, leading to cell cycle arrest, DNA repair or apoptosis. Activity of ATM protein is under tight control, and mutation of ATM can cause disease such as Ataxia telangiectasia (AT) and cancers.
Immunogen:   A synthetic peptide from the internal region of ATM which includes the mutation of R3008H, human origin.
Applications:   ELISA, WB, IHC
Recommended Dilutions:   
ELISA: 1:1000-1:5000
WB: 1:100-1:1000
IHC: 1:50-1:500
Concentration:   1 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:   IgG
Purity:   Purified from ascites
Preservative: No
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity:  Recognizes ATM(R3008H), but not wild type ATM protein from vertebrates.
Storage Conditions:   Store at -20°C. Avoid repeated freezing and thawing

Western blot:  

Western blot analysis of recombinant ATM(R3008H) and wild type proteins.

Purified His-tagged ATM(R3008H) protein (amino acids 2400-3056, lane 2) and corresponding wild type protein (lane 1) were blotted with Anti-ATM(R3008H) mouse monoclonal antibody (Cat. #26140).

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