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cAMP mAb (No Acetylation)

5/5

$495.00

Cat.#:  26002-2

   Size:   30 µl

In Stock

          Product Description          
cAMP mAb (No Acetylation)
Cat. #:   26002-2
Size:  30 µL
Description:   Anti-cAMP Mouse Monoclonal Antibody
Background: cAMP is a ubiquitous second messenger mediating cellular responses to various exogenous and endogenous signaling molecules. cAMP regulates physiological processes by activating protein kinases, gating specific ion channels, modulating cellular cyclic nucleotide concentrations through phosphodiesterases, and activating Epac (exchange protein directly activated by cAMP). The conversion of ATP to cAMP is catalyzed by adenylyl cyclases (ACs). The major family of ACs in mammals is the transmembrane ACs which have nine isoforms and could be activated by G protein Gs and/or Ca2+/calmodulin. There is also one soluble AC which could be modulated by bicarbonate and/or Ca2+.
Immunogen:   cAMP
Applications:   ELISA, WB, IHC
Recommended Dilutions:    ELISA 1:1000-1:5000 WB 1:500-1:2000
Concentration:    1 mg/ml
Host Species:   Mouse
Format:   Liquid
Clonality:   Monoclonal
Isotype:    IgG
Purity:   Purified from ascites
Preservative:  No
Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Storage Conditions:   Store at -20°C. Avoid repeated freezing and thawing
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          Publications          
01. Phosphodiesterase 10A (PDE10A) as a novel target to suppress β-catenin and RAS signaling in epithelial ovarian cancer
J Ovarian Res. 2022
02. Botrytis cinerea G Protein β Subunit Bcgb1 Controls Growth, Development and Virulence by Regulating cAMP Signaling and MAPK Signaling
J Fungi (Basel). 2021
03. Endogenous sulfur dioxide is a novel inhibitor of hypoxia-induced mast cell degranulation
J Adv Res. 2021
04. Glucocorticoids Elevate Pseudomonas aeruginosa Binding to Airway Epithelium by Upregulating Syndecan-1 Expression
Front Microbiol. 2021
05. Lipid biosynthesis mediated by the cyclic adenosine monophosphate (cAMP) signaling pathway in Chlorella pyrenoidosa under salt-induced osmotic stress
Renewable Energy, 2021
06. Maternal intake restriction programs the energy metabolism, clock circadian regulator and mTOR signals in the skeletal muscles of goat offspring probably via the protein kinase A-cAMP-responsive element-binding proteins pathway
Anim Nutr. 2021
07. Matrine Impairs Platelet Function and Thrombosis and Inhibits ROS Production
Front Pharmacol. 2021
08. MoWhi2 regulates appressorium formation and pathogenicity via the MoTor signalling pathway in Magnaporthe oryzae
Mol Plant Pathol. 2021
09. Serotonin receptor 4 in the hippocampus modulates mood and anxiety
Mol Psychiatry. 2021
10. Theacrine, a Potent Antidepressant Purine Alkaloid from a Special Chinese Tea, Promotes Adult Hippocampal Neurogenesis in Stressed Mice
J Agric Food Chem. 2021
11. Two forms of G protein-coupled estrogen receptor 1 in the ricefield eel: Expression and functional characterization in relation to ovarian follicle development
Gen Comp Endocrinol. 2021
12. Urocortins exhibit differential effects on PGE2 and PGF2α output via CRHR2 in human myometrium
Reproduction. 2021
13. Dual-activation of cAMP production through photo-stimulation or chemical stimulation
Methods Mol Biol. 2020
14. Homogeneous single-label cGMP detection platform for the functional study of nitric oxide-sensitive (soluble) guanylyl cyclases and cGMP-specific phosphodiesterases
Methods Mol Biol. 2020
15. Inhibition of DRG-TRPV1 upregulation in myocardial ischemia contributes to exogenous cardioprotection
J Mol Cell Cardiol. 2020
16. A systematic screen of conserved Ralstonia solanacearum effectors reveals the role of RipAB, a nuclear‐localized effector that suppresses immune responses in potato
Mol Plant Pathol. 2019
17. An improved method for isolation of mitochondria from cell lines that enables reconstitution of calcium-dependent processes
Anal Biochem. 2019
18. Expression patterns of C1ql4 and its cell-adhesion GPCR Bai3 in the murine testis and functional roles in steroidogenesis
FASEB J. 2019
19. Glucagon-like peptide-1 attenuates endothelial barrier injury in diabetes via cAMP/PKA mediated down-regulation of MLC phosphorylation
Biomed Pharmacother. 2019
20. Identification of expression and function of the glucagon-like peptide-1 receptor in colonic smooth muscle
Peptides. 2019
21. Luminescence-activated nucleotide cyclase regulates spatial and temporal cAMP synthesis
J Biol Chem. 2019
22. The cyclase-associated protein ChCAP is important for regulation of hyphal growth, appressorial development, penetration, pathogenicity, conidiation, intracellular cAMP level, and stress tolerance in Colletotrichum higginsianum
Plant Sci. 2019
23. A Type IIb, but Not Type IIa, GnRH Receptor Mediates GnRH-Induced Release of Growth Hormone in the Ricefield Eel
Front Endocrinol (Lausanne). 2018
24. Natriuretic peptide receptor 2 (NPR2) localized in bovine oocyte underlies a unique mechanism for C-type natriuretic peptide (CNP)-induced meiotic arrest
Theriogenology. 2018
25. DHA induces apoptosis of human malignant breast cancer tissues by the TLR-4/PPAR-α pathways
Oncol Lett. 2018
26. Improving heterologous expression of porcine follicle-stimulating hormone in Pichia pastoris by integrating molecular strategies and culture condition optimization
Appl Microbiol Biotechnol. 2018
27. N-octanoylated ghrelin peptide inhibits bovine oocyte meiotic resumption
Gen Comp Endocrinol. 2018
28. Environmental and genetic regulation of white-opaque switching in Candida tropicalis
Mol Microbiol. 2017
29. Influence of cell confluence on the cAMP signalling pathway in vascular smooth muscle cells
Cell Signal. 2017
30. Influence of dopamine D1 receptor Ala229Thr polymorphism on receptor signal transduction
中国临床药理学与治疗学. 2017
31. Integration of the tricarboxylic acid (TCA) cycle with cAMP signaling and Sfl2 pathways in the regulation of CO2 sensing and hyphal development in Candida albicans
PLoS Genet. 2017
32. Multifaceted Roles of the Ras Guanine-Nucleotide Exchange Factor ChRgf in Development, Pathogenesis, and Stress Responses of Colletotrichum higginsianum
Phytopathology. 2017
33. Zebrafish phosvitin-derived peptide Pt5 inhibits melanogenesis via cAMP pathway
Fish Physiol Biochem. 2017
34. A cardiac mitochondrial cAMP signaling pathway regulates calcium accumulation, permeability transition and cell death
Cell Death Dis. 2016
35. Characterization and expression of soluble guanylate cyclase in skins and melanocytes of sheep
Acta Histochem. 2016
36. Dietary flavonoid luteolin attenuates uropathogenic Escherichia. Coli invasion of the urinary bladder
Biofactors. 2016
37. Hypoxia-Inducible Factor-2α Limits Natural Killer T Cell Cytotoxicity in Renal Ischemia/Reperfusion Injury
J Am Soc Nephrol. 2016
38. MoRad6-mediated ubiquitination pathways are essential for development and pathogenicity in Magnaporthe oryzae
Environ Microbiol\. 2016
39. Nuclear translocation of nuclear factor kappa B is regulated by G protein signaling pathway in arsenite-induced apoptosis in HBE cell line
Environ Toxicol. 2016
40. RNA polymerase III component Rpc9 regulates hematopoietic stem and progenitor cell maintenance in zebrafish
Development. 2016
41. The effects of IGF1 on the melanogenesis in alpaca melanocytes in vitro
In Vitro Cell Dev Biol Anim. 2016
42. Comparative Effects of Urocortins and Stresscopin on Cardiac Myocyte Contractilit
J Mol Cell Cardiol. 2015
43. Effect of dobutamine on lung aquaporin 5 in endotoxine shock-induced acute lung injury rabbit
J Thorac Dis. 2015
44. Identification of a novel microRNA important for melanogenesis in alpaca (Vicugna pacos)
J Anim Sci. 2015
45. Positive Effect of Carbon Sources on Natural Transformation in Escherichia coli: Role of Low-Level Cyclic AMP (cAMP)-cAMP Receptor Protein in the Derepression of rpoS
J Bacteriol. 2015
46. Alteration of vascular reactivity in heart failure: Role of phosphodiesterases type 3 and 4
Br J Pharmacol. 2014
47. cAMP–PKA inhibition of SK3 channel reduced both Ca2+ entry and cancer cell migration by regulation of SK3–Orai1 complex
Pflugers Arch. 2014
48. Comparative study of somatostatin-human serum albumin fusion proteins and natural somatostatin on receptor binding, internalization and activation
PLoS One. 2014
49. Immunomodulating effects of casein-derived peptide QEPVL and QEPV on lymphocytes in vitro and in vivo
Food Funct. 2014
50. Inactivation of the Carney complex gene 1 (PRKAR1A) alters spatiotemporal regulation of cAMP and cAMP-dependent protein kinase: a study using genetically encoded FRET-based reporters
Hum Mol Genet. 2014
51. Ischemia/Reperfusion-Induced CHOP Expression Promotes Apoptosis and Impairs Renal Function Recovery: The Role of Acidosis and GPR4
PLoS One. 2014
52. Sex is a major determinant of neuronal dysfunction in Neurofibromatosis Type 1
Ann Neurol. 2014
53. Three genes encoding citrate synthases in Saccharopolyspora erythraea are regulated by the global nutrient-sensing regulators GlnR, DasR, and CRP
Mol Microbiol. 2014
54. Opposing HDAC4 nuclear fluxes due to phosphorylation by β adrenergic activated PKA or by activity or Epac activated CaMKII in skeletal muscle fibres
J Physiol. 2013
55. Subendocardial Increase in Reactive Oxygen Species Production Affects Regional Contractile Function in Ischemic Heart Failure
Antioxid Redox Signal. 2013
56. Transgenic rescue of defective Cd36 enhances myocardial adenylyl cyclase signaling in spontaneously hypertensive rats
Pflugers Arch. 2013
57. Uncoupling of M1 muscarinic receptor/G-protein interaction by amyloid beta(1-42)
Neuropharmacology. 2013
58. Agonist-Dependent And -Independent Dopamine-1-Like Receptor Signalling Differently Regulates Downstream Effectors
Handb Exp Pharmacol. 2012
59. Antiarrhythmic effect of prolonged morphine exposure is accompanied by altered myocardial adenylyl cyclase signaling in rats
Pharmacol Rep. 2012
60. Heterogeneity in relaxation of different sized porcine coronary arteries to nitrovasodilators: role of PKG and MYPT1
Pflugers Arch. 2012
61. Natriuretic peptides block synaptic transmission by activating phosphodiesterase 2A and reducing presynaptic PKA activity
Proc Natl Acad Sci U S A. 2012
62. Structural basis of anthrax edema factor neutralization by a neutralizing antibody
Biochem Biophys Res Commun. 2012
63. Retigeric Acid B Attenuates the Virulence of Candida albicans via Inhibiting Adenylyl Cyclase Activity Targeted by Enhanced Farnesol Production
PLoS One. 2012
64. Molt-inhibiting hormone from Chinese mitten crab (Eriocheir sinensis): Cloning, tissue expression and effects of recombinant peptide on ecdysteroid secretion of YOs
Gen Comp Endocrinol. 2011