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CCR4 (DMC297) IgG1 Chimeric mAb

Anti-CCR4 (DMC297) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28196

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28196
Product Name:   Anti-CCR4(DMC297) IgG1 Chimeric Monoclonal Antibody
Synonyms:   CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4; HGCN:14099; K5-5
Description:    Anti-CCR4 antibody(DMC297) IgG1 Chimeric Monoclonal Antibody
Background:    The protein encoded by this gene belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine – MIP-1; RANTES; TARC and MCP-1. Chemokines are a group of small polypeptide; structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development; homeostasis; and function of the immune system; and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CCR4
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-CCR4 (DMC297) on Expi293 cells transfected with human CCR4 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).