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Human CCR4 Full Length Protein

Human CCR4 Full Length Protein-Synthetic Nanodisc


Cat.#:  11008

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11008
Product Name:   Human CCR4 Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CC-CKR-4; CD194; ChemR13; CKR4; CMKBR4
Target:    CCR4
UNIPROT ID:    P51679
Description:    Human CCR4 full length protein-synthetic nanodisc
Background:     The protein belongs to the G-protein-coupled receptor family . It is a receptor for the CC chemokine – MIP-1, RANTES, TARC and MCP-1. Chemokines are a group of small polypeptide, structurally related molecules that regulate cell trafficking of various types of leukocytes. The chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis.
Species/Host:    HEK293
Molecular Weight:    The human full length CCR4 Protein has a MW of 41.4 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag CCR4-Nanodisc (0.2 µg/per well). Serial diluted anti-CCR4 monoclonal antibody (28089) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CCR4 monoclonal antibody binding with CCR4-Nanodisc is 40.3ng/ml.

Figure2. Human CCR4-Nanodisc, Flag Tag on SDS-PAGE