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Human CCR9 Full Length Protein

Human CCR9 Full Length Protein-Synthetic Nanodisc


Cat.#:  11042

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11042
Product Name:   Human CCR9 Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   CC-CKR-9; CDw199; GPR-9-6; GPR28
Target:    CCR9
UNIPROT ID:    P51686
Description:    Human CCR9 full length protein-synthetic nanodisc
Background:     The protein is a G protein-coupled receptor with seven transmembrane domains that belongs to the beta chemokine receptor family. Chemokines and their receptors are key regulators of thymocyte migration and maturation in normal and inflammation conditions. This gene is differentially expressed in T lymphocytes of the small intestine and colon, and its interaction with chemokine 25 contributes to intestinal intra-epithelial lymphocyte homing to the small intestine. This suggests a role for this gene in directing immune responses to different segments of the gastrointestinal tract. This gene and its exclusive ligand, chemokine 25, are overexpressed in a variety of malignant tumors and are closely associated with tumor proliferation, apoptosis, invasion, migration and drug resistance. This gene maps to the chemokine receptor gene cluster.
Species/Host:    HEK293
Molecular Weight:    The human full length CCR9 protein has a MW of 42.0 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag CCR9-Nanodisc (0.2 µg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CCR9-Nanodisc is 3.205ng/ml.

Figure2. Human CCR9-Nanodisc, Flag Tag on SDS-PAGE