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Human CD37 Full Length Protein

Human CD37 Full Length Protein-Synthetic Nanodisc


Cat.#:  11023

   Size:   50 μg

In Stock

          Product Description          
Cat.#:     11023
Product Name:   Human CD37 Full Length Protein
Size :    10 µg, 50 µg and 100 µg
Synonyms:   GP52-40; TSPAN26
Target:    CD37
UNIPROT ID:    P11049
Description:    Human CD37 full length protein-synthetic nanodisc
Background:     The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
Species/Host:    HEK293
Molecular Weight:    The human full length CD37 protein has a MW of 31.7 kDa
Formulation & Reconstitution:    Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Figure1. Elisa plates were pre-coated with Flag Tag CD37-Nanodisc (0.2 µg/per well). Serial diluted anti-CD37 monoclonal antibody (28055) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CD37 monoclonal antibody binding with CD37-Nanodisc is 23.06ng/ml.

Figure2. Human CD37-Nanodisc, Flag Tag on SDS-PAGE

Figure3. WB analysis of Human CD37-Nanodisc with anti-CD37 monoclonal antibody (28055), followed by Goat Anti-Human IgG HRP at 1/5000 dilution