Subtotal:
$445.00
$445.00
| Cat.#: 28312 | ||||
| Product Name: Anti-CD38(DM28) Rabbit Monoclonal Antibody | ||||
| Synonyms: T10; cADPr hydrolase 1 | ||||
| Description: Anti-CD38 antibody(DM28) Rabbit Monoclonal Antibody | ||||
| Background: CD antigen CD38 is also known as ADP-ribosyl cyclase 1; which belongs to the ADP-ribosyl cyclase family. CD38 is expressed at high levels in pancreas; liver; kidney; brain; testis; ovary; placenta; malignant lymphoma and neuroblastoma. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD to ADP-ribose. These reaction products are essential for the regulation of intracellular Ca2 . The loss of CD38 function is associated with impaired immune responses; metabolic disturbances; and behavioral modifications. The CD38 protein is a marker of cell activation. It has been connected to HIV infection; leukemias; myelomas; solid tumors; type II diabetes mellitus and bone metabolism. CD38 has been used as a prognostic marker in leukemia. | ||||
| Applications: ELISA; Flow Cyt | ||||
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 | ||||
| Host Species: Rabbit | ||||
| Isotype: Rabbit IgG | ||||
| Purification: Purified from cell culture supernatant by affinity chromatography | ||||
| Species Reactivity: Human CD38 | ||||
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. | ||||
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). | ||||
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