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CD44 (DMC269) IgG1 Chimeric mAb

Anti-CD44 (DMC269) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28177

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28177
Product Name:   Anti-CD44(DMC269) IgG1 Chimeric Monoclonal Antibody
Description:    Anti-CD44 antibody(DMC269) IgG1 Chimeric Monoclonal Antibody
Background:    The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions; cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands; such as osteopontin; collagens; and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation; recirculation and homing; hematopoiesis; and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms; however; the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein; and may be related to tumor metastasis.
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CD44
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-CD44 (DMC269) on Expi293 cells transfected with human CD44 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).