| Cat.#: 11013 |
| Product Name: Human CD63 Full Length Protein |
| Size : 10 µg, 50 µg and 100 µg |
| Synonyms: LAMP-3; ME491; MLA1; OMA81H; TSPAN30 |
| Target: CD63 |
| UNIPROT ID: P08962 |
| Description: Human CD63 full length protein-synthetic nanodisc |
| Background: The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms. |
| Species/Host: HEK293 |
| Molecular Weight: The human full length CD63 protein has a MW of 25.6 kDa |
| Formulation & Reconstitution: Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Figure1. Elisa plates were pre-coated with Flag Tag CD63-Nanodisc (0.2 µg/per well). Serial diluted anti-CD63 monoclonal antibody (28219) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CD63 monoclonal antibody binding with CD63-Nanodisc is 94.22ng/ml. | 
Figure2. Human CD63-Nanodisc, Flag Tag on SDS-PAGE |
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