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CDH17 (DMC485) IgG1 Chimeric mAb

Anti-CDH17 (DMC485) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28261

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28261
Product Name:   Anti-CDH17(DMC485) IgG1 Chimeric Monoclonal Antibody
Synonyms:   CDH16; HPT-1; HPT1
Description:    Anti-CDH17 antibody(DMC485) IgG1 Chimeric Monoclonal Antibody
Background:    This gene is a member of the cadherin superfamily; genes encoding calcium-dependent; membrane-associated glycoproteins. The encoded protein is cadherin-like; consisting of an extracellular region; containing 7 cadherin domains; and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts; acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. Alternative splicing results in multiple transcript variants. [provided by RefSeq; Jan 2009]
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human CDH17
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-CDH17 (DMC485) on Expi293 cells transfected with human CDH17 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).