Cat.#: 28467 |
Product Name: Anti-CEACAM5(DM122) Rabbit Monoclonal Antibody |
Synonyms: CEACAM-5;CD66e;CEA;Meconium antigen 100 |
Description: Anti-CEACAM5 antibody(DM122) Rabbit Monoclonal Antibody |
Background: This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally; the encoded protein may regulate differentiation; apoptosis; and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. |
Applications: ELISA; Flow Cyt |
Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 |
Host Species: Rabbit |
Isotype: Rabbit IgG |
Purification: Purified from cell culture supernatant by affinity chromatography |
Species Reactivity: Human CEACAM5 |
Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
 Figure 1. ELISA plate pre-coated by 1 µg/ml (100 µl/well) Human CEACAM5 protein, His tagged protein 11194 can bind Rabbit anti-CEACAM5 monoclonal antibody (clone: DM122) in a linear range of 0.1-50 ng/ml. |  Figure 2. Flow cytometry analysis with Anti-CEACAM5 (DM122) on Expi293 cells transfected with human CEACAM5(Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram). |
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