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EDA (DMC388) IgG1 Chimeric mAb

Anti-EDA (DMC388) IgG1 Chimeric Monoclonal Antibody


Cat.#:  28206

   Size:   100 μg

In Stock

          Product Description          
Cat.#:   28206
Product Name:   Anti-EDA(DMC388) IgG1 Chimeric Monoclonal Antibody
Synonyms:   ED1; EDA2
Description:    Anti-EDA antibody(DMC388) IgG1 Chimeric Monoclonal Antibody
Background:    The protein encoded by this gene is a type II membrane protein that can be cleaved by furin to produce a secreted form. The encoded protein; which belongs to the tumor necrosis factor family; acts as a homotrimer and may be involved in cell-cell signaling during the development of ectodermal organs. Defects in this gene are a cause of ectodermal dysplasia; anhidrotic; which is also known as X-linked hypohidrotic ectodermal dysplasia. Several transcript variants encoding many different isoforms have been found for this gene.
Applications:    Flow Cyt
Recommended Dilutions:    Flow Cyt 1:100
Host Species:    Rabbit
Isotype:    Rabbit:Human Fc chimeric IgG1
Purification:    Purified from cell culture supernatant by affinity chromatography
Species Reactivity:    Human EDA
Constituents:    Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization.
Storage & Shipping:    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).

Figure 1. Flow cytometry analysis with Anti-EDA (DMC388) on Expi293 cells transfected with human EDA (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).