| Cat.#: 28033 |
| Product Name: Anti-TIGIT (Etigilimab) Monoclonal Antibody |
| Synonyms: TIGIT;SIG9;STM3 |
| Description: Anti-TIGIT (etigilimab ) Monoclonal Antibody |
| Background: Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Applications: ELISA; Flow Cyt |
| Recommended Dilutions: ELISA 1:5000-10000; Flow Cyt 1:100 |
| Host Species: Humanized |
| Isotype: IgG1 |
| Purification: Purified from cell culture supernatant by affinity chromatography |
| Species Reactivity: Human TIGIT |
| Constituents: Lyophilized from sterile PBS, pH 7.4. 5 % – 8% trehalose is added as protectants before lyophilization. |
| Storage & Shipping: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). |
Figure 1. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human TIGIT, His tagged protein 11309 can bind Anti-TIGIT Neutralizing antibody in a linear range of 0.13-16.0 ng/ml. |
Figure 2. ELISA plate pre-coated by 2 µg/ml (100 µl/well) Human TIGIT, mFc tagged protein 11308 can bind Anti-TIGIT Neutralizing antibody in a linear range of 0.13-16.0 ng/ml. |
Figure 3. HEK293 cell line transfected with irrelevant protein (B) and human TIGIT protein (A) were surface stained with anti-TIGIT neutralizing antibody 1 µg/ml (etigilimab) followed by Alexa 488-conjugated anti-human IgG secondary antibody. |
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